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T9033 Sigma

Thapsigargin

≥98% (HPLC), solid film

Description

Biochem/physiol Actions

Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations.

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New TruPAGE™ Pre-cast Polyacrylamide Gels

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