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T9034 Sigma

Taurocholic acid sodium salt hydrate

BioXtra, ≥95% (TLC)

Synonym: 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate

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Properties

Related Categories Anionic Detergents, Bile Acid Metabolism, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
description   anionic
InChI Key   RDAJAQDLEFHVNR-NEMAEHQESA-M
product line   BioXtra
assay   ≥95% (TLC)
mol wt   micellar avg mol wt 2100
aggregation number   4
impurities   ≤0.005% Phosphorus (P)
  ≤0.1% Insoluble matter
CMC   3-11 mM(20-25°C)
solubility   H2O: soluble0.2 M, clear, colorless to faintly yellow
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.01%
  Mg: ≤0.005%
  NH4+: ≤0.1%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Application

Anionic detergent used for protein solubilization.

Taurocholic acid, a bile acid, may be used in studies of the physiological effects of bile salts on intestinal function and bacterial flora development.

Packaging

1, 5, 25, 100 g in poly bottle

Biochem/physiol Actions

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Price and Availability


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Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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