• USA Home
  • T9145 - Thyroglobulin from bovine thyroid

EMAIL THIS PAGE TO A FRIEND
T9145 Sigma

Thyroglobulin from bovine thyroid

(For Gel Filtration Chromatography)

Purchase

Properties

Related Categories Antibodies, Antibody Purification and Characterization, Carrier Proteins, Supplementary Products
mol wt   mol wt ~670 kDa
storage temp.   −20°C
Gene Information   cow ... TG(280706)

Description

Application

Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.

Biochem/physiol Actions

Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.

Price and Availability


Antibody Explorer

Explore with Confidence

Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

A Validated Amino Acid Analysis Assay for Accurate Quantification of Stable Isotope Labeled Protein Reference Materials: SIL Thyroglobulin Case Study

With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance. Certifi...
Kevin Ray1, Pegah R. Jalili1, Mark Angeles1, James J. Walters1, Isil Dilek2, and Uma Sreenivasan2

1 - MilliporeSigma, St. Louis, MO
2 - MilliporeSigma, Round Rock, TX
Keywords: Amino acid analysis, Clinical, Fractionation, High performance liquid chromatography, Mass spectrometry, PAGE, Protein extraction

Characterization of Clinically-Relevant Stable Isotope Labeled Recombinant Proteins For Use As Internal Standards in Quantitative MS Workflows

Methods for quantification of clinical protein biomarkers by mass spectrometry demand a high level of analytical quality. Procedures must be developed to minimize and control experimental variations ...
Kevin Ray, Pegah Jalili, James Walters, David Rhee
Sigma-Aldrich, St. Louis, MO
Keywords: Clinical, Fractionation, Mass spectrometry, Protein extraction

HPLC Analysis of Four Proteins on Zenix® SEC-300, Comparison of Column Internal Diameter

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Four Proteins on Zenix® SEC-300, Comparison of Column Internal Diameter
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards by Size Exclusion on Zenix® as Affected by Pore Size: 100Å vs. 300Å

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards by Size Exclusion on Zenix® as Affected by Pore Size: 100Å vs. 300Å
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 at Low Flow Rate

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 at Low Flow Rate
Keywords: Chromatography, Diffusion, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Arginine

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Arginine
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Potassium Chloride

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Potassium Chloride
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Sodium Perchlorate

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Sodium Perchlorate
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 in the Presence of a Denaturant

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 in the Presence of a Denaturant
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® Columns, Effect of Pore Size

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® Columns, Effect of Pore Size
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (15 cm column)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (15 cm column)
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (30 cm column)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (30 cm column)
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® and SRT® SEC-300, Comparison of Particle Size and Column I.D.

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® and SRT® SEC-300, Comparison of Particle Size and Column I.D.
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of a Protein Mixture on Zenix® SEC-150 versus Zenix® SEC-300, Effect of Pore Size on Resolution

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of a Protein Mixture on Zenix® SEC-150 versus Zenix® SEC-300, Effect of Pore Size on Resolution
Keywords: Chromatography, Clinical, High performance liquid chromatography, Size-exclusion chromatography

Protein Molecular Weight Calibration Curve on Zenix® Size Exclusion Columns, Effect of Pore Size

From our library of Articles, Sigma-Aldrich presents Protein Molecular Weight Calibration Curve on Zenix® Size Exclusion Columns, Effect of Pore Size
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?