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  • T9577 - Anti-p8/TTD-A (N-terminal) antibody produced in rabbit

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T9577 Sigma

Anti-p8/TTD-A (N-terminal) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-C6orf175 TFB5, Anti-Chromosome 6 open reading frame 175, Anti-GTF2H5, Anti-General transcription factor IIH, polypeptide 5, Anti-TFIIH basal transcription factor complex, TTDA subunit, Anti-TGF2H5, Anti-TTDA transcription factor IIH, 8-kd subunit

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Gene Regulation, Antibodies to Common Transcription Factors, Antibodies to Transcription Factors,
species reactivity   mouse, human, rat
application(s)   indirect immunofluorescence: 1:200-1:400 using paraformaldehyde-fixed HEK-293T cells, over-expressing human p8/TTD-A
  western blot: 1:250-1:500 using lysates of CHO or HEK-293T over-expressing human p8/TTD-A
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~8 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GTF2H5(404672)
mouse ... Gtf2h5(66467)
rat ... Gtf2h5(502227)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 13-30 of human p8/TTD-A, conjugated to KLH. The corresponding sequence is identical in rat and differs by one amino acid in mouse.

Antigen Background

p8/TTD-A (N-terminal) encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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