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  • T9702 - Anti-p8/TTD-A (C-terminal) antibody produced in rabbit

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T9702 Sigma

Anti-p8/TTD-A (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym: Anti-C6orf175 TFB5, Anti-Chromosome 6 open reading frame 175, Anti-GTF2H5, Anti-General transcription factor IIH, polypeptide 5, Anti-TFIIH basal transcription factor complex, TTDA subunit, Anti-TGF2H5, Anti-TTDA transcription factor IIH, 8-kd subunit

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Gene Regulation, Antibodies to Common Transcription Factors, Antibodies to Transcription Factors,
species reactivity   rat, human, mouse
application(s)   indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK-293T cells over-expressing human p8/TTD-A
  western blot: 1-2 μg/mL using HEK-293T over-expressing human p8/TTD-A
clone   polyclonal
concentration   ~1 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt ~35 kDa (tagged fused protein)
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GTF2H5(404672)
mouse ... Gtf2H5(66467)
rat ... Gtf2hr(502227)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 56-71 of human p8/TTD-A, conjugated to KLH. The corresponding sequence is identical in rat and mouse.

Antigen Background

p8/TTD-A (C-terminal) encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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T9577 Anti-p8/TTD-A (N-terminal) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

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