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U0633 Sigma

Urokinase from human urine

lyophilized powder, ≥500 units/mg protein

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Description

Biochem/physiol Actions

Urokinase expression and invasiveness suppression by urinary trypsin inhibitor acts through MEK/ERK/c-Jun-dependent signaling pathways.

Unit Definition

One unit will activate that amount of plasminogen which will produce a ΔA275 of 1.0 per ml per minute at pH 7.5 at 37 °C, when measuring perchloric acid soluble products from α-casein (1 cm light path).

Physical form

Lyophilized from 1 mL of 50 mM Tris-HCl, pH 7.4 with 100 mM NaCl, 0.1% PEG 6000, and 200 mM mannitol

Physical properties

High molecular weight form migrating at 54 kDa by SDS-PAGE under non-reducing conditions

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
OB8900000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

Related Products

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Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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