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U109 Sigma

R(+)-UH-301 hydrochloride

solid

Synonym: R(+)-5-Fluoro-8-Hydroxy-DPAT hydrochloride, R(+)-5-Fluoro-8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalene hydrochloride

  • CAS Number 127126-18-5

  • Empirical Formula (Hill Notation) C16H24FNO · HCl

  • Molecular Weight 301.83

  •  MDL number MFCD00210227

  •  PubChem Substance ID 24278137

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Properties

Related Categories Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
InChI Key   FKUVCCNCUAFKAH-UTONKHPSSA-N
form   solid
optical activity   [α]25/D +81.4°, c = 0.30 in methanol(lit.)
color   white
solubility   H2O: slightly soluble
  ethanol: soluble
Gene Information   human ... HTR1A(3350)

Description

Caution

Hygroscopic, photosensitive

Packaging

1, 5 mg in glass bottle

Preparation Note

R(+)-UH-301 hydrochloride is soluble in ethanol and is slightly soluble in water.

Biochem/physiol Actions

R(+)-UH-301 hydrochloride is a potent and selective 5-HT1A serotonin receptor agonist. R(+)-UH-301 is also known to function as an antinociceptive agent, as it has been shown to significantly decrease formalin-induced flinching in rats.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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