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U115 Sigma

U-101958 maleate salt

solid

Synonym: 1-Benzyl-4-aminomethyl-N-[(3′-isopropoxy)-2′-pyridyl]piperidine maleate salt

  • Empirical Formula (Hill Notation) C21H29N3O · C4H4O4

  • Molecular Weight 455.55

  •  MDL number MFCD01529984

  •  PubChem Substance ID 24277945

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   KPYPLDPMBWPEBO-BTJKTKAUSA-N
form   solid
color   off-white
solubility   DMSO: soluble11 mg/mL
  ethanol: soluble2.7 mg/mL
  H2O: soluble3 mg/mL
Gene Information   human ... DRD4(1815)

Description

Packaging

25 mg in poly bottle

5 mg in glass bottle

Preparation Note

U-101958 maleate salt is soluble in water (at 3 mg/mL), ethanol (2.7 mg/mL), and DMSO (11 mg/mL).

Biochem/physiol Actions

U-101958 maleate salt is a selective D4 dopamine receptor antagonist. Studies have reported that U-101958 maleate cannot inhibit bromocriptine-mediated [3H]thymidine incorporation in opossum kidney (OK) cells.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety Information

RIDADR 
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3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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