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U116 Sigma

U-99194 maleate salt

≥98% (HPLC), solid

Synonym: 5,6-Dimethoxy-2-(di-n-propylamino)indan maleate salt

  • CAS Number 234757-41-6

  • Empirical Formula (Hill Notation) C17H27NO2 · C4H4O4

  • Molecular Weight 393.47

  •  MDL number MFCD01529985

  •  PubChem Substance ID 24277946

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Description

Preparation Note

U-99194 maleate salt is soluble in water at a concentration >5 mg/ml.

Application

U-99194 maleate has been used as a dopaminergic antagonist to study its effects on immobility episodes and yawning frequency in rats.

Biochem/physiol Actions

U-99194 is a putative D3 antagonist with a 30-fold preference for the dopamine D3 vs. D2 receptor.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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