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U4375 Sigma

Uridine 5′-diphospho-N-acetylglucosamine sodium salt


Synonym: UDP-N-acetylglucosamine, UDP-GlcNAc, UDPAG



Biochem/physiol Actions

Donor substrate for transfer of GlcNAc to the dolichol precursor in the synthesis of N-glycans. UDP-GlcNAc also functions as the source of GlcNAc attached to serine/threonine residues by O-GlcNAc transferase (OGT) in O-GlcNAc signaling.


1 g in poly bottle

25, 100, 500 mg in poly bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. U4375.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability

All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Protocols & Articles


Glycosyltransferases: Tools for Synthesis and Modification of Glycans

The presence of multiple functional groups and stereocenters in complex carbohydrates makes them challenging targets for the organic chemist. Chemical synthesis research has not yielded robust, autom...
BioFiles 2007, 2.1, 2.
Keywords: Acylations, Bacterial conjugations, Biochemistry, Catalysis, Enzyme activity, Fucosylation, Gene expression, Glycosylations, Methods, Organic synthesis, Protocols, Sequences, Solvents, Type


Glycosyltransferases are specific for the type of linkage (α or β), and the linkage position of the glycoside bond formed [e.g. α(1→3) or β(1→4)]. Glycosyltransferases were initially considered to be...
Glycobiology Analysis Manual, 2nd Edition
Keywords: Catalysis, Cell signaling, Enzyme activity, Glycosylations, Pharmaceutical, Type

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers


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