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U6631 Sigma

Urocortin rat

≥97% (HPLC), powder

DOWNLOAD MSDS (PDF)

  • CAS Number 171543-83-2

  • Empirical Formula (Hill Notation) C206H338N62O64

  • Molecular Weight 4707.26

  •  MDL number MFCD00678232

Properties

Related Categories CRF, Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins,
assay   ≥97% (HPLC)
form   powder
solubility   1% acetic acid: >1 mg/mL, clear, colorless
storage temp.   −20°C
Gene Information   rat ... Ucn(29151)

Description

Amino Acid Sequence

Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2

Biochem/physiol Actions

Binds to CRF receptor types 1, 2α, and 2β; stimulates cAMP accumulation from cells transfected with these receptors. Acts in vitro to release ACTH from rat anterior pituitary cells.

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