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U7128 Sigma

Uricase from Arthrobacter globiformis

lyophilized powder, 15-30 units/mg protein (biuret)

Synonym: Urate oxidase, Urate:O2 oxidoreductase

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Description

Packaging

100 units in serum bottle

Unit Definition

One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.

Biochem/physiol Actions

Molecular weight: 4 × ~32 KDa (tetramer)
Isoelectric point: is 4.64
KM value (uric acid as substrate): ~ 0.01 mM
The optimum pH for activity: 8.5-9.5
The optimum pH for stability: 6.0-9.5

Zn and Cu were shown to inhibit the activity of uricase.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YU7100000
Protocols & Articles

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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