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U8632 Sigma

Ubiquitin-Carrier Protein H5a, GST-tagged human

≥95% (SDS-PAGE), liquid

Synonym: UbcH5a human

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Cell Stress and Refolding, Enzymes, Inhibitors, and Substrates,
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE)
form   liquid
mol wt   mol wt 47 kDa
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... UBE2D1(7321), UBE2N(7334)

Description

Biochem/physiol Actions

Human homologs of the yeast UBC4/5 family and play many important regulatory roles in inflammation and cancer.

Mediates the degradation of a myriad of short-lived regulatory proteins including the tumor suppressor p53 in the presence of E6/E6-AP or MDM2, the c-Fos transcription factor, and the signal-induced ubiquitination of IκBα, UBC5 is an essential gene in yeast.

General description

Manufactured for Sigma by Boston Biochem., Inc.

Physical form

Solution in 50 mM HEPES, pH 8.0, 100 mM NaCl, 1 mM DTT in 10% glycerol.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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