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UCL 1684 ditrifluoroacetate hydrate

Synonym: 6,12,19,20,25,26-hexahydro- 5,27:13,18:21,24-Trietheno-11,7-metheno-7H-dibenzo[b,m][1,5,12,16]tetraazacyclotricosine-5,13-diium ditrifluoroacetate hydrate

  • CAS Number 201147-19-5 (anhydrous)

  • Linear Formula (C34H30N4)2+ · (C2F3O2-)2 · xH2O

  • Molecular Weight 720.66 (anhydrous basis)

  •  PubChem Substance ID 24900684

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Description

Biochem/physiol Actions

UCL 1684 ditrifluoroacetate hydrate is a potent non-peptide blocker of the apamin-sensitive Ca2+-activated K+ channel.

Packaging

5, 25 mg in glass bottle

Preparation Note

UCL 1684 ditrifluoroacetate hydrate is soluble in water at 10 mg/ml.

Application

UCL 1684 ditrifluoroacetate hydrate has been used for analyzing the mechanism for ammonium-mediated displacement of the protonated analyte from analyte-trifluoroacetic acid (TFA) ion-pair. UCL 1684 has also been used as a potassium channel inhibitor to study CNP (C-type natriuretic peptide)-induced relaxations in pig coronary arteries.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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