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U9382 Sigma

Ubiquitin-Carrier Protein H10 human

≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution

Synonym: UbcH10

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,
recombinant   expressed in E. coli (histidine-tagged)
assay   ≥95% (SDS-PAGE)
form   buffered aqueous glycerol solution
mol wt   mol wt ~20 kDa
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... UBE2C(11065)

Description

General description

Manufactured for Sigma by Boston Biochem., Inc.

Physical form

Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.

Application

Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.

Biochem/physiol Actions

In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.

Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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