• USA Home
  • V3003 - Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse

EMAIL THIS PAGE TO A FRIEND
V3003 Sigma

Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse

clone 260.4, KDR-2, ascites fluid

Synonym: Anti-KDR, Anti-VEGFR-2, Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 antibody produced in mouse

Properties

Related Categories Alphabetical Index, Angiogenesis, Antibodies, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   human
application(s)   immunohistochemistry (frozen sections): suitable
  indirect ELISA: suitable
  western blot: 1:500 using insect cell culture supernatant expressing human extracellular recombinant VEGFR or VEGF Receptor-2 (KDR, FLK-1)/FC Chimera human, recombinant
clone   260.4, KDR-2, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... KDR(3791)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

purified recombinant human extracellular VEGF receptor-2 (KDR).

General description

Vascular Endothelial Growth Factor Receptor-2 (VEGF R2) also known as KDR or Flk-1is a member of protein kinase superfamily and have high affinity for vascular endothelial growth factor-A (VEGF-A), hence facilitates most of the endothelial growth and survival signals from VEGF-A. It also plays a pivotal role in vascular development, vascular permeability, embryonic hematopoiesis and regulation of angiogenesis. Monoclonal anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody can be used for studying the differential tissue expression as well as intracellular localization of receptor in normal and neoplastic tissues. It can also be used in immunoblotting. Mouse anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody reacts specifically with human VEGF receptor-2 but not with Flt4, Flt1 or platelet-derived growth factor receptor (PDGF-R1).

Antigen Background

The KDR receptor (VEGFRa), defining marker of hematopoietic stem cells (HSCs), distinguishes pluripotent HSCs from lineage-committed progenitor HSCs.

Specificity

Reacts specifically with human VEGF receptor-2. This clone has also been termed 260.4. It does not recognize Flt1 (VEGFR-1), Flt4 (VEGFR-3), or platelet-derived growth factor receptor (PDGF-R).

Application

Monoclonal anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody can be used in many immunochemical assays like ELISA and immunohistochemistry for the localization of VEGF Receptor-2 (KDR).

Price and Availability


Detect Your Unseen Protein

All labs need water

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?