V3265 Sigma

VU0029767

≥98% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: (E)-2-(4-Ethoxyphenylamino)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide

  • CAS Number 326001-01-8

  • Empirical Formula (Hill Notation) C21H21N3O3

  • Molecular Weight 363.41

  •  MDL number MFCD01206089

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cholinergics, Neuroscience, Neurotransmission,
assay   ≥98% (HPLC)
form   powder
color   gray-brown
solubility   DMSO: >10 mg/mL
storage temp.   room temp

Description

Biochem/physiol Actions

VU0029767 is a selective, positive allosteric modulator at the muscarinic M1 acetylcholine receptor. It shifts concentration-dependent response to acetylcholine at least five-fold, but does not compete at the ACh binding site. VU0029767 also potentiates the effects of allosteric agonist TBPB.

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