|Related Categories||Berberis sp., Biochemicals and Reagents, Cofactor, Hordeum vulgare (Barley), Isoprenoid,|
|density||0.984 g/mL at 25 °C(lit.)|
1, 5, 10 g in glass bottle
Vitamin K1 (Phylloquinone) is a lipid soluble polycyclic aromatic ketone used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. V3501.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediatesvitamin K-dependent intracellular antioxidant function. Westhofen P, Watzka M, et al. J. Biol. Chem. 286, 15085-15094, (2011)
Effects of long-term vitamin K(1) (phylloquinone) or vitamin K(2) (menaquinone-4) supplementation on body composition and serum parameters in rats. Sogabe N, Maruyama R, et al. Bone 48, 1036-1042, (2011)
c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition. Carr BI, Wang Z, Wang M, et al. Cancer Biol. Ther. 12, 531-538, (2011)
Synthesis of new vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists: insights into the biological role of the side chain part of vitamin K. Yoshitomo Suhara et al J. Med. Chem. 54, 4918-22, (2011)
Corp MSDS 1 (2), 3609:C / FT-IR 2 (2), 2485:A / RegBook 1 (2), 1683:J / Sax 6, 1933 / Sigma FT-IR 1 (2), 973:B / Structure Index 1, 267:C:1
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