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V7264 Sigma

Venlafaxine hydrochloride

≥98% (HPLC), powder

Synonym: (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor

  • CAS Number 99300-78-4

  • Empirical Formula (Hill Notation) C17H27NO2 · HCl

  • Molecular Weight 313.86

  •  MDL number MFCD03658865

  •  PubChem Substance ID 329829062

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Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
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References

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