(±)-Vigabatrin
DOWNLOAD MSDS (PDF)Synonym:
(±)-γ-Vinyl-GABA,
(±)-4-Aminohexenoic acid,
(R,S)
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CAS Number 60643-86-9
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Empirical Formula (Hill Notation) C6H11NO2
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Molecular Weight 129.16
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MDL number MFCD00274577
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PubChem Substance ID 24278202
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Popular Documents: Specification Sheet (PDF)
Properties
| Related Categories | Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, |
| Gene Information | human ... GABBR1(2550), GABBR2(9568), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562) |
Description
Biochem/physiol Actions
Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. V8261.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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Animal models of the epilepsies. Fisher, R.S. Brain Res. Brain Res. Rev. 14, 245, (1989)
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