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W4262 Sigma

1400W dihydrochloride

>98%, solid

Synonym: N-([3-(Aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride

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Properties

Related Categories Application Index, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   WDJHSQZCZGPGAA-UHFFFAOYSA-N
assay   >98%
form   solid
storage condition   desiccated
originator   GlaxoSmithKline
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... NOS1(4842), NOS2(4843), NOS3(4846)

Description

Biochem/physiol Actions

1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS).

Packaging

10 mg in glass bottle

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

Peer-Reviewed Papers
15

References

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