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X2628 Sigma

Xestospongin C

film

Synonym: XeC

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Regulators,
InChI Key   PQYOPBRFUUEHRC-HCKQMYSWSA-N
form   film
color   colorless
solubility   DMSO: soluble
shipped in   dry ice
storage temp.   −20°C

Description

General description

Synthetic form of the macrocyclic bis-1-oxaquinolizidine isolated from the Okanowan marine sponge.

Packaging

10, 50 μg in glass bottle

Package under nitrogen, tightly sealed.

Biochem/physiol Actions

Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. Reversibly blocks bradykinin- and carbamylcholine- Ca2+ efflux from the endoplasmic reticulum stores.

Features and Benefits

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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