X4626 Sigma

XTT sodium salt

powder, BioReagent, suitable for cell culture

Synonym: 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt

  • CAS Number 111072-31-2

  • Empirical Formula (Hill Notation) C22H16N7NaO13S2

  • Molecular Weight 673.52

  •  MDL number MFCD00083517

  •  PubChem Substance ID 24902150



XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage,2 in testing antimicrobial susceptibility of staphylococci,3 and in Candida biofilm research.4 Limitations to the XTT assay have been reported.5


In living cells, XTT is metabolically reduced to produce a colorimetric, water-soluble formazan product.

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