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Z0878 Sigma

Zaprinast

solid

Synonym: 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, G Proteins and Cyclic Nucleotides, Phosphodiesterase Inhibitors More...
InChI Key   REZGGXNDEMKIQB-UHFFFAOYSA-N
form   solid
color   white
solubility   45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.11 mg/mL
  DMSO: soluble10 mg/mL
  H2O: insoluble
Gene Information   human ... PDE2A(5138), PDE4A(5141), PDE4B(5142), PDE4D(5144)

Description

Biochem/physiol Actions

Selective inhibitor of cGMP-specific phosphodiesterases V and VI (PDE5/6) and an agonist at the G protein-coupled receptor 35 (GPR35).

Packaging

25, 100 mg in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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