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Z101 Sigma

Zimelidine dihydrochloride

solid

Synonym: (Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine dihydrochloride

  • CAS Number 61129-30-4

  • Empirical Formula (Hill Notation) C16H17BrN2 · 2HCl

  • Molecular Weight 390.15

  •  MDL number MFCD00069358

  •  PubChem Substance ID 24278138

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Properties

Related Categories Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   CXGURXWCQYHDIR-ULPVBNQHSA-N
form   solid
color   white
solubility   0.1 M HCl: soluble45 mg/mL
  H2O: soluble66 mg/mL
originator   AstraZeneca
Gene Information   human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Description

Biochem/physiol Actions

Serotonin transport blocker; antidepressant.

Legal Information

Sold with the permission of Astra AB.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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