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Z3003 Sigma

Zardaverine

phosphodiesterase inhibitor

Synonym: 6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism, Enzyme Inhibitors,
InChI Key   HJMQDJPMQIHLPB-UHFFFAOYSA-N
potency   1.1 μM IC50 (for PDE IV)
  2.5 μM IC50 (for PDE III)
Gene Information   human ... PDE3A(5139), PDE3B(5140), PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144), PDE5A(8654), PDE7A(5150)
rat ... Pde2a(81743), Pde4a(25638)

Description

Biochem/physiol Actions

Selective inhibitor of phosphodiesterase III/IV (PDE3/4).

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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