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Z364223 Sigma

The Telomere

  •  ISBN-10 0-19-963600-1

  •  ISBN-13 978-0-19-963600-6

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publication info   D. Kipling, Oxford University Press, 1995, 202 pp., soft cover
mfr. no.   Oxford University Press

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General description

Telomeres, specialized structures at the ends of chromosomes, are involved in genetic phenomena with a potential role in the aging and malignant transformation of cells. This book introduces the central questions concerning telomeres, examines experimental data, and provides a large number of recent references.

Table of Contents

1. Introduction
2. The Cytology of the Telomere
3. Telomere Structure
4. Telomerase
5. Telomere Proteins
6. Genome Rearrangements and Telomeres
7. Human Telomere Loss, Aging, and Cancer
8. Chromatin Structure and Position Effects
9. Structure and Maintenance of Drosophila Telomeres
10. Telomeres and Mammalian Genome Analysis

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