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Z378305 Sigma

Bioseparation of Proteins: Unfolding/Folding and Validation

  •  ISBN-10 0-12-614040-5

  •  ISBN-13 978-0-12-614040-8



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publication info   A. Sadana, Academic Press, 1997, 360 pp., hard cover
mfr. no.   Elsevier


General description

A detailed critical review of literature on effectiveness, economics, and validation of bioseparation processes for drugs and other biological products. Key contents include: stability under various separation conditions case studies on methods development protein refolding and inactivation mechanisms. Coverage includes classical as well as modern bioseparation techniques.

Table of Contents

Introduction. Steps in Bioseparation Processes. High Resolution Fractionation Processes. Protein Inactivation during Bioseparation. Adsorption Influence on
Bioseparation and Inactivation. Process Monitoring and Validation. Applications and Economics of Bioseparation. Protein Inactivation Avoidance and Refolding
during Bioseparation. Subject Index.

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