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Z705659 Sigma

Synthesis of Essential Drugs

  •  ISBN-10 0-444-52166-6

  •  ISBN-13 978-0-444-52166-8



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publication info   R. Vardanyan and V. Hruby, Elsevier, 2006, 634 pp., hard cover
mfr. no.   Elsevier


General description

This book represents an effort to meet a long overdue need of compiling information of 30 years of work in the area of the synthesis of medicinal drugs. This effort fills obvious gaps that exist in the literature of drug synthesis. The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis. It covers generic drugs that are included in the WHO’s "Essential List of Drugs."

Table of Contents

1. General Anesthetics
2. Local Anesthetics
3. Analgesics
4. Hypnotics and Sedatives
5. Anxiolitics (Tranquilizers)
6. Antipsycotics (Neuroleptics)
7. Antidepressants
8. Central Nervous System Stimulants
9. Antiepileptics
10. Anti-Parkinson Drugs
11. Adrenegic (Sympatomimetic) Drugs
12. Adrenoblocking Drugs
13. Cholinomimetics
14. Anticholinergic Drugs
15. Muscle Relaxants
16. Antihistamine Drugs
17. Cardiac Glycosides and Other Inotropes
18. Drugs for Tachyarrhytmias
19. Antianginal Drugs
20. Agents Used in Hyperlipoproteinemia
21. Diuretics
22. Antihypertensive Drugs
23. Drugs for Treating of Pulmonary Diseases
24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics
25. Thyroid and Parathyroid Drugs
26. Insulin and Synthetic Hypoglycemic Agents
27. Corticosteroids
28. Female Sex Hormones
29. Male Sex Hormones and Anabolics
30. Antineoplastic Agents
31. Immunopharmacologic Drugs
32. Antibiotics
33. Antimicrobials
34. Antimicobacterials
35. Antifungal Drugs
36. Antiviral Drugs
37. Antiprotozoal Drugs
38. Antihelmint Drugs

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