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53269-U Supelco

SupelMIP® SPE - Fluoroquinolones

bed wt. 25 mg, volume 3 mL, pk of 50

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Properties

Related Categories Analytical/Chromatography, Sample Preparation & Purification, Solid Phase Extraction (SPE), SupelMIP Molecular Imprinted Polymers, SupelMIP SPE - Fluoroquinolones More...
composition   bed wt., 25 mg
packaging   pk of 50
volume   3 mL
matrix active group   SupelMIP® phase

Description

Application

Developed and optimized for the extraction of fluoroquinilones (FQL) from a variety of sample matrixes including bovine kidney, honey, and milk.

Example FQLs include sarafloxacin, norfloxacin, enrofloxacin, and ciprofloxacin.

Features and Benefits

• Highly selective SPE for trace analysis in complex matrices
• Achieve lower detection limits
• Significant time and cost savings
• Improved MS-compatibility

General description

SupelMIP SPE phases were developed by MIP Technologies AB, which is one of the leading authorities and commercial pioneers of molecular imprinted polymers for process scale separations, analytical chromatography, and sample preparation.

The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.

By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.

Visit www.sigma-aldrich.com/supelmip to learn more.

Legal Information

SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


All labs need water

Non-Sterile Millex Syringe Filters
Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles

Articles

Molecularly Imprinted Polymer SPE for the Highly Selective Extraction of Fluoroquinolones from Bovine Kidney

Fluoroquinolones (FQLs) are a class of broad-spectrum antibiotics heavily used in veterinary and human medicine. Widespread usage of this class of antibiotics has resulted in the emergence of resista...
Anna-Karin Wihlborg1, Olga Shimelis2,and An Trinh2
Reporter US Vol 27.1
Keywords: Antibiotics, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Solid phase extractions, Veterinary

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