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54805 Supelco

Disposable PD-10 Desalting Column

Properties

Related Categories Analytical/Chromatography, HiTrap & PD-10 Cartridges, Resins & LC Separation Media, Resins and Media
material   polypropylene (with polyethylene frit)
packaging   pkg of 30 ea
storage temp.   2-8°C

Description

Frequently Asked Questions

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Application

PD-10 desalting columns have been used to purify reduced Alemtuzumab (Campath, Berlex) humanized IgG1 rat monoclonal antibody from excess phospine, which is being developed for the treatment of chronic lymphocytic leukemia, autoimmune disease and for the prevention of transplant rejection.

General description

The PD-10 desalting columns contain Sephadex® G-25 for gel filtration (size exclusion) of biomolecules. Globular compounds pass quickly through the column. Compounds, such as salts, pass through the column slowly. The column actually separates two classes of compounds by their molecular weight, thus desalting the protein of interest.

Legal Information

Sephadex is a registered trademark of GE Healthcare

Price and Availability

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