130672
Aldrich

N-Hydroxysuccinimide

98%

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1 of 1

Synonym

1-Hydroxy-2,5-pyrrolidinedione

HOSu

Molecular Formula

C₄H₅NO₃

Molecular Weight

115.09

CAS Number

6066-82-6

Beilstein Registry Number

113913

MDL number

MFCD00005516

PubChem Substance ID

24847975

EG/EC Number

228-001-3

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Descriptions

Frequently Asked Questions

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Application

Additive used in the carbodiimide method for improved amidations¹ and peptide couplings.²

Used to activate a carboxyl group for amide bond formation.^3,⁴

Packaging

25, 100, 250 g in poly btl

5 g in glass btl

Properties

assay

98%

95-98 °C(lit.)

References

Cited Reference

1. Anal. Biochem. 218, 87, (1994) abstract

2. Polycyclic Aromat. Compd. 3, 781, (1993)

3. J. Am. Chem. Soc. 128, 15072, (2006) abstract

4. J. Pept. Sci. 12, 653, (2006) abstract

Beilstein

Beil. 21,V,9,498

Fieser

Fieser 1,487 / Fieser 9,246

reference

Aldrich MSDS 1, 1080:A / Corp MSDS 1 (1), 1962:B / FT-IR 2 (1), 1351:A / FT-IR 1 (1), 796:B / FT-NMR 1 (1), 1300:B / IR-Spectra (3), 472:B / IR-Spectra (2), 418:G / NMR-Reference 2 (1), 667:C / RegBook 1 (1), 931:I / Sigma FT-IR 1 (2), 646:B / Structure Index 1, 145:A:2

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... Coupling > Active Esters/Additives

FT-IR Raman

FT-NMR

MSDS

Specification Sheet

Certificate of Analysis

Certificate of Origin

More Information