270911
Aldrich

Sodium cholate hydrate

98%

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Synonym

Cholalic acid sodium salt

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt

Molecular Formula

C₂₄H₃₉NaO₅ · xH₂O

Molecular Weight

430.55 (anhydrous basis)

CAS Number

206986-87-0

Beilstein Registry Number

3582354

MDL number

MFCD00150749

EG/EC Number

206-643-5

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Descriptions

Application

Non-denaturing detergent used for extraction of membrane proteins.

Packaging

25, 100 g in glass btl

Properties

assay

98%

optical activity

[α]20/D +31.3°, c = 0.5 in H₂O

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

CMC

9-15 mM(20-25°C)

HLB

References

Reference

A. Helenius Meth. Enzymol. 56, 734, (1979)

Hori, H., et al., Isolation and characterization of two 20S proteasomes from the endoplasmic reticulum of rat liver microsomes. J. Biochem. (Tokyo) 126, 722-730, (1999)

Ozols, J., Preparation of membrane fractions. Meth. Enzymol. 182, 225-235, (1990)

J.C. Gordon Eur. J. Pharmacol., Molec. Pharmacol. Sec. 188, 313, (1990)

L.M. Hjelmeland, A. Chrambach Meth. Enzymol. 104, 305, (1984)

C.V. Nicchitta, G. Blobel Cell 60, 259, (1990) abstract

Beilstein

Beil. 10,III,2166 / Beil. 10,IV,2073

reference

RegBook 1 (2), 2869:J / Sigma FT-IR 1 (1), 1222:A / Structure Index 1, 459:A:8

Safety

WGK Germany

3-9

Related Categories

... Sterols > Bile acids and Derivatives

... Organic Building Blocks > Carboxylic Acid Salts

FT-IR Raman

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Specification Sheet

Certificate of Analysis

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