Hoveyda-Grubbs Catalyst 1^st Generation 

Olefin metathesis catalyst.^3,4

Catalyst used in ring-closing metathesis with concomitant cis-vicinal dihyroxylation.¹ Also employed in a pivotal, macrocyclic ring-closing metathesis in the multi-step synthesis of an HCV protease inhibitor.²

NO BULK ORDERS

100, 500 mg in glass btl

2 g in glass btl

US Patent No. 6,111,121 and foreign equivalents apply. Sale of this product conveys to the buyer a limited-use research license. For full details of this license please see sigma-aldrich.com/materialicense. For questions, please contact us at aldrich@sial.com or Materia at info@materia-inc.com.

195-197 °C(lit.)

1. Angew. Chem. Int. Ed. 45, 1900, (2006)

2. J. Org. Chem. 71, 7133, (2006) abstract

3. Heterocycles 63, 5-8, (2004)

4. Tet. 59, 6545-6558, (2003)

3

569747, Grubbs Catalyst, 2^nd Generation

579726, Grubbs Catalyst, 1st generation