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MilliporeSigma

M68423

N-Methyl-phenethylamine

99%

Synonym(s):

N-Methyl-2-phenylethylamine

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M68423-5ML

$110.00

M68423-25ML

$427.00

$110.00


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About This Item

Linear Formula:
C6H5CH2CH2NHCH3
CAS Number:
Molecular Weight:
135.21
Beilstein/REAXYS Number:
636347
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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Quality Level

assay

99%

form

liquid

refractive index

n20/D 1.516 (lit.)

bp

203 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

SMILES string

CNCCc1ccccc1

InChI

1S/C9H13N/c1-10-8-7-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3

InChI key

SASNBVQSOZSTPD-UHFFFAOYSA-N

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1 of 4

This Item
128945427470M79603
assay

99%

assay

99%

assay

99%

assay

99%

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

100

bp

203 °C (lit.)

bp

197-200 °C (lit.)

bp

171 °C/15 mmHg (lit.)

bp

202 °C (lit.), 81-82 °C/10 mmHg (lit.)

refractive index

n20/D 1.516 (lit.)

refractive index

n20/D 1.533 (lit.)

refractive index

n20/D 1.563 (lit.)

refractive index

n20/D 1.47 (lit.)

form

liquid

form

liquid

form

liquid

form

liquid

density

0.93 g/mL at 25 °C (lit.)

density

0.962 g/mL at 20 °C (lit.)

density

1.01 g/mL at 25 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

Application

N-Methyl-phenethylamine can be used as a reactant:
  • To synthesize N-methyl-phenethylamine based tertiary amines by reacting with different alkyl halides in the presence of triphenylphosphine (TPP) and diisopropylazocarboxylate (DIAD) via N-alkylation reaction.[1]
  • To fabricate photochemically stable, super-sensitive, and highly selective fluorescent film for the detection of N-methamphetamine (an illicit drug).[2]
  • To prepare biologically active squaric acid N-hydroxylamide amide derivatives.[3]

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Efficient synthesis of tertiary amines from secondary amines
Michio K, et al.
Tetrahedron Letters, 47, 4871-4875 (2006)
Fabrication of a new fluorescent film and its superior sensing performance to N-methamphetamine in vapor phase
H Meixia, et al.
Sensors and Actuators B, Chemical, 227 (2016)
Aron D Mosnaim et al.
Neurochemical research, 38(4), 842-846 (2013-02-08)
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78
Xulin Tan et al.
Journal of separation science, 30(12), 1888-1892 (2007-07-20)
A novel chiral stationary phase (CSP) for HPLC was prepared by bonding (R)-1-phenyl-2-(4-methylphenyl)ethylamine amide derivative of (S)-valine to aminopropyl silica gel through a 2-amino-3,5-dinitro-1-carboxamido-benzene unit. The CSP was used for the separation of some amino acid derivatives and pyrethroid insecticides
K A Moore et al.
Drug and alcohol dependence, 39(2), 83-89 (1995-08-01)
Methamphetamine is a popular drug of abuse, readily synthesized in clandestine laboratories. Illicitly obtained methamphetamine is frequently impure, containing various purposefully added diluents and adulterants, as well as impurities of manufacture and origin. Few impurities have been studied in vivo

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