β-Carotene 

As a probe of lipid domains of reconstituted human plasma low-density lipoprotein¹

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

BioChemika

purum

≥97.0% (UV)

≤0.001% heavy metals

≤0.2% loss on drying

176-184 °C (dec.)

chloroform: 10 mg/mL, clear, dark orange-red

dry ice

−20°C

1. G.C. Chen et al. Biochemistry 19, 4706, (1980) abstract

Palozza, P., et al., Prooxidant effects of beta-carotene in cultured cells. Mol. Aspects Med. 24, 353-362, (2003)

Seifried, H.E., et al., The antioxidant conundrum in cancer. Cancer Res. 63, 4295-4298, (2003)

Paolini, M., et al., β-carotene: a cancer chemopreventive agent or a co-carcinogen?. Mutat. Res. 543, 195-200, (2003)

Woodall, A.A., et al., Carotenoids and protection of phospholipids in solution or in liposomes against oxidation by peroxyl radical. Biochim. Biophys. Acta 1336, 575-586, (1997)

Krinsky, N.I., The antioxidant and biological properties of the carotenoids. Ann. N.Y. Acad. Sci. 854, 443-447, (1998)

Merck 13,1866

Beil. 5,IV,2617

1

FI0329500

218 °F

103 °C