27028
Fluka

Sodium cholate hydrate

BioChemika, ≥96.0% (dry matter, NT)

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Synonym

Cholalic acid sodium salt

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt

Molecular Formula

C₂₄H₃₉NaO₅ · xH₂O

Molecular Weight

430.55 (anhydrous basis)

CAS Number

206986-87-0

Beilstein Registry Number

3582354

MDL number

MFCD00150749

EG/EC Number

206-643-5

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Descriptions

Application

Non-denaturing detergent used for extraction of membrane proteins.

Properties

product line

BioChemika

assay

≥96.0% (dry matter, NT)

optical activity

[α]20/D +35±2°, c = 0.6% in ethanol (dry matter)

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

total impurities

~4% water

CMC

9-15 mM(20-25°C)

solubility

H₂O: 0.1 M, clear

anion traces

chloride (Cl^-): ≤50 mg/kg

sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg

Cd: ≤5 mg/kg

Co: ≤5 mg/kg

Cr: ≤5 mg/kg

Cu: ≤5 mg/kg

Fe: ≤5 mg/kg

K: ≤50 mg/kg

Mg: ≤5 mg/kg

Mn: ≤5 mg/kg

Ni: ≤5 mg/kg

Pb: ≤5 mg/kg

Zn: ≤5 mg/kg

HLB

References

Reference

A. Helenius Meth. Enzymol. 56, 734, (1979)

J.C. Gordon Eur. J. Pharmacol., Molec. Pharmacol. Sec. 188, 313, (1990)

C.V. Nicchitta, G. Blobel Cell 60, 259, (1990) abstract

L.M. Hjelmeland, A. Chrambach Meth. Enzymol. 104, 305, (1984)

Hori, H., et al., Isolation and characterization of two 20S proteasomes from the endoplasmic reticulum of rat liver microsomes. J. Biochem. (Tokyo) 126, 722-730, (1999)

Ozols, J., Preparation of membrane fractions. Meth. Enzymol. 182, 225-235, (1990)

Beilstein

Beil. 10,III,2166 / Beil. 10,IV,2073

reference

RegBook 1 (2), 2869:J / Sigma FT-IR 1 (1), 1222:A / Structure Index 1, 459:A:8

Safety

WGK Germany

3-9

Related Categories

... Sterols > Bile acids and Derivatives

MSDS

Certificate of Analysis

More Information