L-Glutathione reduced 

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

10 mg in autosmp vl

≥99%

192-195 °C (dec.)(lit.)

2-8°C

Pompella, A., et al., The changing faces of glutathione, a cellular protagonist. Biochem. Pharmacol. 66, 1499-1503, (2003)

Pastore, A., et al., Analysis of glutathione: implication in redox and detoxification. Clin. Chim. Acta 333, 19-39, (2003)

Townsend, D.M., and Tew, K.D., The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22, 7369-7375, (2003)

Merck 13,4488

Beil. 4,IV,3165

FT-IR 2 (1), 1334:C / FT-IR 1 (1), 787:D / FT-NMR 1 (1), 1283:B / IR-Spectra (3), 467:F / IR-Spectra (2), 414:G / RegBook 1 (1), 919:L / Sax 6, 1478 / Sigma FT-IR 1 (1), 359:B / Structure Index 1, 143:B:1

2

MC0556000