Sulfanilamide 

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

≥99%

164-166 °C(lit.)

mouse ... Car13(71934), Car5a(12352)

human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)

Meneau, I. et al.,, Pneumocystis jiroveci dihydropteroate synthase polymorphisms confer resistance to sulfadoxine and sulfanilamide in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 48, 2610-6, (2004) abstract

Merck 13,9010

Beil. 14,IV,2658

FT-IR 2 (2), 3294:B / FT-IR 1 (2), 532:B / FT-NMR 1 (2), 1636:B / IR-Spectra (3), 1176:D / IR-Spectra (2), 1024:H / NMR-Reference 2 (2), 851:D / RegBook 1 (2), 2243:A / Sax 6, 2480 / Sigma FT-IR 1 (1), 716:C / Structure Index 1, 352:D:2

3

WO8400000