T8656
Sigma-Aldrich

Thiourea

ACS reagent, ≥99.0%

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Synonym

Sulfourea

Thiocarbamide

Molecular Formula

NH₂CSNH₂

Molecular Weight

76.12

CAS Number

62-56-6

Beilstein Registry Number

605327

MDL number

MFCD00008067

PubChem Substance ID

24900549

EG/EC Number

200-543-5

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Descriptions

Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Properties

grade

ACS reagent

assay

≥99.0%

ign. residue

≤0.1%

loss

≤0.5% loss on drying

170-176 °C(lit.)

solubility

H₂O: passes test

References

Reference

Pasquali, C.,et al., Preparative two-dimensional gel electrophoresis of membrane proteins. Electrophoresis 18, 2573-2581, (1997)

Fialka, I., et al., Subcellular fractionation of polarized epithelial cells and identification of organelle-specific proteins by two-dimensional gel electrophoresis. Electrophoresis 18, 2582-2590, (1997)

Rabilloud, T., Use of thiourea to increase the solubility of membrane proteins in two-dimensional electrophoresis. Electrophoresis 19, 758-760, (1998)

Merck

Merck 13,9443

Beilstein

Beil. 3,IV,342

reference

Aldrich MSDS 1, 1706:D / Corp MSDS 1 (2), 3338:B / FT-IR 2 (1), 1400:B / FT-IR 1 (1), 827:A / IR-Spectra (3), 491:E / IR-Spectra (2), 435:B / RegBook 1 (1), 971:B / Sax 6, 1672 / Sigma FT-IR 1 (2), 930:B / Structure Index 1, 151:D:3

Safety

Hazard Codes

Xn,N

Risk Statements

22-40-51/53-63

Safety Statements

36/37-61

WGK Germany

RTECS

YU2800000