Atrial Natriuretic Peptide fragment 4-24 frog 

Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.

≥97% (HPLC)

African clawed frog ... anf-A(394320)

−20°C

Sakata, J., et al. Biochem. Biophys. Res. Commun. 155, 1338, (1988) abstract

Potter, L.R., and Hunter, T., Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B. Methods 19, 506-520, (1999)

Gonzalez Bosc, L.V., Effects of atrial natriuretic peptide in the gut. Peptides 21, 875, (2000)

Palluk, R., et al., Atrial natriuretic factor. Life Sci. 36, 1415-1425, (1985)

Thibault, G., et al., Regulation of natriuretic peptide secretion by the heart. Annu. Rev. Physiol. 61, 193, (1999)

Potter, L.R. and Hunter, T., Structural and functional evolution of the natriuretic peptide system in vertebrates. Int. Rev. Cytol. 194, 1, (2000)

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