A145
Sigma

1-Allyl-3,7-dimethyl-8-sulfophenylxanthine

solid

Molecular Formula

C₁₆H₁₆N₄O₅S

Molecular Weight

376.39

CAS Number

149981-25-9

MDL number

MFCD00083167

PubChem Substance ID

24277693

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Descriptions

Biochem/physiol Actions

Weak A₂ adenosine receptor antagonist.

Properties

form

solid

color

white

solubility

H₂O: soluble

abs.

ε_max/203 nm, methanol 28,200

ε_max/239 nm, methanol 21,900

ε_max/301 nm, methanol 18,200

Gene Information

human ... ADORA2A(135), ADORA2B(136)

References

Reference

Jacobson, et al., Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors. J. Med. Chem. 38, 2639, (1993)

Castanon, et al., Functional coupling of human adenosine receptors to a ligand-dependent reporter gene system. Biochem. Biophys. Res. Commun. 198, 626, (1994) abstract

Safety

WGK Germany

Related Categories

... Nucleosides, Nucleotides, Oligonucleotides > Nucleoside Analogs

MSDS

Certificate of Analysis

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A145 (Sigma)