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Synonym
Acetyl
Molecular Formula
C23H38N7O17P3S · xLi+
Molecular Weight
809.57 (free acid basis)
CAS Number
MDL number
PubChem Substance ID
Descriptions
Biochem/physiol Actions
Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. It is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. It is a positive regulator of pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine.
Preparation Note
Prepared enzymatically
References
Reference
Szutowicz, A., Key role of acetyl-CoA in cytoplasm of nerve terminals in disturbances of acetylcholine metabolism in brain. Folia Neuropathol. 35, 241, (1997)
Decker, K., Bergmeyer, H.U., ed. Meth. Enzym. Anal., (1985) 7, 186-200
Garland P.B., Bergmeyer, H.U., ed. Meth. Enzym. Anal., (1985) 7, 206-211
Beutler, H., Supp, M., Bergmeyer, H.U., ed. Meth. Enzym. Anal., (1984) 2, 329-330
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