A2223
Sigma

Axl/Fc Chimera from mouse

≥90% (SDS-PAGE), recombinant, expressed in mouse NSO cells

MDL number

MFCD03456147

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Descriptions

Analysis Note

Measured by its ability to bind recombinant human Gas6.

Biochem/physiol Actions

Member of a tyrosine kinase receptor subfamily shown to be involved in hematopoiesis, embryonic development, tumorigenesis, and testicular function regulation.

General description

Extracellular domain of mouse Axl (residues 1-443) fused to the C-terminal histidine-tagged Fc region of human IgG1.

Physical form

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline.

Properties

recombinant

expressed in mouse NSO cells

assay

≥90% (SDS-PAGE)

mol wt

calculated mol wt 72.3 kDa

mol wt 100-110 kDa by SDS-PAGE (reducing)

total impurities

Endotoxin, tested

Gene Information

mouse ... Axl(26362)

storage temp.

−20°C

References

Reference

Nagata, K., et al. J. Biol. Chem. 22, 30022, (1996)

Crosier, K.E., and Crosier, P.S. Pathology 29, 131, (1997) abstract

O'Bryan, J.P., et al. Mol. Cell Biochem. 11, 5016, (1991)

Safety

WGK Germany

Related Categories

... Receptor Tyrosine Kinases > Axl

... Protein Phosphorylation > Kinases and Phosphatases

... Tumor Growth Regulation > Oncoproteins

... Cell Signaling Enzymes > Signal Transduction

A2223 - Datasheet (30kb)

MSDS

Certificate of Analysis

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