A2722
Sigma

[Val⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt

≥95% (HPLC), solid

Amino Acid Sequence

Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg

Molecular Formula

C₅₁H₈₂N₁₄O₁₈

Molecular Weight

1179.28

CAS Number

252256-43-2

MDL number

MFCD02684499

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Descriptions

Biochem/physiol Actions

β-secretase substrate corresponding to the Met/Val substitution of the amyloid precursor protein (APP) β-secretase cleavage site.

Properties

assay

≥95% (HPLC)

form

solid

Gene Information

human ... APP(351)

storage temp.

−20°C

References

Reference

Vasser, R., et al., β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE. Science 286, 735, (1999)

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... β Amyloid Peptides > Amyloid Precursor Proteins

... Substrates by Enzyme > beta-Secretase

... Protease Substrates > beta-Secretase

MSDS

Certificate of Analysis

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A2722 (Sigma)

[Val671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt

≥95% (HPLC), solid

[Val⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt