Immunogen
synthetic peptide corresponding to amino acids 22-35 of human β-amyloid (1-40) fragment, conjugated to KLH. This sequence corresponds to amino acids 693-706 of the human amyloid precursor protein APP, and is identical in mouse and rat APP.
Specificity
The antibody specifically recognizes β-amyloid (22-35), β-amyloid (25-35), β-amyloid (1-40), and β-amyloid (1-42) and does not react with β-amyloid (32-35) by ELISA. The antibody detects β-amyloid (1-40) by immunoblotting.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide and 1% bovine serum albumin.
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