A4972
Sigma

DABCYL-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 fragment 661-675−EDANS trifluoroacetate salt

≥97% (HPLC), solid

Amino Acid Sequence

DABCYL-Ile-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-EDANS

Molecular Formula

C₁₀₃H₁₄₆N₂₂O₃₂S

Molecular Weight

2236.45

MDL number

MFCD03453641

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Descriptions

Biochem/physiol Actions

β-secretase substrate.

Properties

assay

≥97% (HPLC)

form

solid

Gene Information

human ... APP(351)

storage temp.

−20°C

References

Reference

Ermolieff, J., et al., Proteolytic activation of Recombinant Pro-memapsin (Pro-b-secretase) Studied with New Fluorogenic Substrates. Biochemistry 39, 12450, (2000)

Safety

Safety Statements

22-24/25

WGK Germany

Related Categories

... β Amyloid Peptides > Amyloid Precursor Proteins

... Substrates by Enzyme > beta-Secretase

... Protease Substrates > beta-Secretase

... Neurodegenerative Disease Peptides > Other Amyloid Protein Fragments

MSDS

Certificate of Analysis

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A4972 (Sigma)

DABCYL-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 fragment 661-675−EDANS trifluoroacetate salt

≥97% (HPLC), solid

DABCYL-[Asn⁶⁷⁰, Leu⁶⁷¹]-Amyloid β/A4 Precursor Protein 770 fragment 661-675−EDANS trifluoroacetate salt