A5751
Sigma

Acetylthiocholine iodide

≥98% (TLC), powder

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Synonym

(2-Mercaptoethyl)trimethylammonium iodide acetate

Molecular Formula

CH₃COSCH₂CH₂N(CH₃)₃I

Molecular Weight

289.18

CAS Number

1866-15-5

Beilstein Registry Number

3916578

MDL number

MFCD00011819

PubChem Substance ID

24891015

EG/EC Number

217-474-1

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Descriptions

Application

Substrate for the colorimetric determination of acetylcholinesterase activity¹

Substrates

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

Properties

assay

≥98% (TLC)

form

powder

color

white

205-210 °C(lit.)

solubility

H₂O: 100 mg/mL

storage temp.

−20°C

References

Cited Reference

1. G.L. Ellman, et al. Biochem. Pharmacol. 7, 88, (1961)

Reference

Puu, G., Comparison of kinetic parameters for acetylthiocholine, soman, ketamine and fasciculin towards acetylcholinesterase in liposomes and in solution. Biochem. Pharmacol. 40, 2209, (1990) abstract

Bannerjee, B., Thermodynamic studies with acetylthiocholine on nicotinic receptors of mammalian skeletal muscle in vitro. Biochem. Pharmacol. 49, 1713, (1995) abstract

Froede, H.C., Direct determination of acetyl-enzyme intermediate in the acetylcholinesterase-catalyzed hydrolysis of acetylcholine and acetylthiocholine. J. Biol. Chem. 259, 11010, (1984) abstract

Puu, G. Biochem. Pharmacol. 40, 2209, (1990)

Froede, H.C. J. Biol. Chem. 259, 11010, (1984)

Bannerjee, B. Biochem. Pharmacol. 49, 1713, (1995)

Beilstein

Beil. 4,IV,1585

reference

Aldrich MSDS 1, 27:C / Corp MSDS 1 (1), 51:B / FT-IR 2 (1), 1131:A / FT-IR 1 (1), 679:C / FT-NMR 1 (1), 1078:B / IR-Spectra (3), 397:A / IR-Spectra (2), 351:D / NMR-Reference 2 (1), 571:C / RegBook 1 (1), 773:N / Sax 6, 120 / Sigma FT-IR 1 (2), 4:C / Structure Index 1, 120:B:8

Safety

Hazard Codes

Risk Statements

21-25-36/37/38

Safety Statements

26-36

RIDADR

UN2811 6.1 /PG 3

WGK Germany

RTECS

FZ9865000

3-8-10