A6402
Sigma

[Asn¹, Val⁵]-Angiotensin II

≥97% (HPLC)

Amino Acid Sequence

Asn-Arg-Val-Tyr-Val-His-Pro-Phe

Molecular Formula

C₄₉H₇₀N₁₄O₁₁

Molecular Weight

1031.17

CAS Number

20071-00-5

MDL number

MFCD00133941

Expand/Collapse All

Descriptions

Biochem/physiol Actions

Angiotensin agonist that has been isolated from kallikrein or renal-extract treated plasma and is involved in the regulation of blood pressure, water consumption, and hydromineral balance in fish.

Properties

assay

≥97% (HPLC)

storage temp.

−20°C

References

Reference

Fuentes, J., and Eddy, F.B., Effect of manipulation of the renin-angiotensin system in control of drinking in juvenile Atlantic salmon (Salmo salar L) in fresh water and after transfer to sea water. J. Comp. Physiol. 167, 438-443, (1997)

Conlon, J.M., et al., Production of [Asn1, Val5] angiotensin II and [Asp1, Val5] angiotensin II in kallikrein-treated trout plasma (T60K). Peptides 17, 527-530, (1996) abstract

Liu, Y.J., et al., Evidence that [Sar1]angiotensin II behaves differently from angiotensin II at angiotensin AT1 receptors in rabbit aorta. Eur. J. Pharmacol. 235, 9-15, (1993) abstract

Butler, D.G., et al., Angiotensin I- and II- and norepinephrine-mediated pressor responses in an ancient holostean fish, the bowfin (Amia calva). Gen. Comp. Endocrinol. 98, 289-302, (1995) abstract

Safety

WGK Germany