A6778
Sigma

Angiotensin Converting Enzyme from rabbit lung

lyophilized powder, 2.0-6.0 units/mg protein (modified Warburg-Christian)

Synonym

ACE

Peptidyl-dipeptidase A

Peptidyldipeptide Hydrolase

CAS Number

9015-82-1

Enzyme Commission (EC) Number

3.4.15.1 ( BRENDA | IUBMB )

MDL number

MFCD00130325

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Descriptions

Biochem/physiol Actions

Removes C-terminal dipeptides from susceptible substrates, e.g., angiotensin I and bradykinin.

Quality

May contain traces of sodium chloride.

Unit Definition

One unit will produce 1.0 μmole of hippuric acid from Hippuryl-His-Leu per min in 50 mM HEPES and 300 mM NaCl at pH 8.3 at 37 °C.

Properties

form

lyophilized powder

storage temp.

−20°C

References

Reference

Cushman, D.W. and Cheung, H.S, Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem. Pharmacol. 20, 1637-1648, (1971)

Safety

WGK Germany

3

F

10-21

Related Products

Substrate

F7131, N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

H1635, N-Hippuryl-His-Leu hydrate

H1763, Hippuryl-Gly-Gly

H4884, Hippuryl-His-Leu acetate salt

Inhibitor

C4042, Captopril

A0773, Angiotensin Converting Enzyme Inhibitor

B0507, Bradykinin potentiator B

B0632, Bradykinin potentiator C

F5017, Foroxymithine microbial

S6633, N-Succinyl-L-proline

Related Categories

... Selective Proteolytic Enzymes > Angiotensin Converting Enzyme

... Neuropeptides > Angiotensin Metabolism

... General Metabolic Enzymes > General Metabolic Enzymes A-H

... Proteolytic Enzymes and Substrates > Proteolytic Enzymes

... 3.x.x.x Hydrolases > 3.4.x.x Peptidases

A6778 - Product Information Sheet (51kb)

A6778 - Enzyme Assay (51kb)

MSDS

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Certificate of Analysis

Certificate of Origin

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A6778 (Sigma)

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